Diffuse Bio

Generative AI for protein design

2.6Score#464 of 999 agents#7 of 16 in Scientist

Why it ranks #464

Diffuse Bio, an AI scientist from YC W23, ranks #464 of 999 AI agents and #7 of 16 in Scientist, with a score of 2.6 of 10. Data as of 3 Oct 2026.

The score adds four parts, each 0 to 10, by weight. Every point comes from public evidence. How scoring works ·

Proof 0 × 30% 0.0
Scale 4 × 30% 1.2
Momentum 2 × 25% 0.5
Autonomy 6 × 15% 0.9
= 2.6

Proof
Do customers use it? 30% of the score
0
No public claims of customers or revenue yet.
Not found: revenue or growth (+4), named customers (+3), a customer result (+2), a customer count (+2), work done at scale (+2)
Scale
Is there a real company behind it? 30% of the score
4
10 people.
- +4
  10 people on its YC page10 to 19 people
Not found: funding round in its news (+3)
Momentum
Is it shipping and growing now? 25% of the score
2
Shows hiring.
- +2
  Hiring: 2 open rolesML Research Engineer, Software EngineerYC page
Not found: launch YC post in the last 6 months (+3), new traction claim in the last 6 months (+2), funding news in the last year (+2), a batch in the last year (it is YC Winter 2023) (+1)
Autonomy
How much of the job does it do on its own? 15% of the score
6
Supervised agent: takes actions in other systems; a person approves key steps.
- +6
  Level 2 of 4: Supervised agentTakes actions in other systems; a person approves key steps.
What the model read
- Acts in other systems: 8% likely
- Finishes whole tasks: 12% likely
- Calls itself an agent: 2% likely
- Level 1 from the model's reading of its pages; the evidence review found, with quotes, that its AI acts in the work, so the level is 2
Level 2: Takes actions in other systems; a person approves key steps.

About Diffuse Bio

Diffuse is building generative AI for protein design. Our mission is to build AI systems that engineer new and useful proteins with unprecedented control and accuracy. Our team has been behind breakthroughs in AI protein design for the past 7 years, including the first experimental validation of AI-generated proteins and diffusion models for protein structure and sequence.